kaspmedПрикаспийский вестник медицины и фармацииTitle2712-8164ФГБОУ ВО Астраханский ГМУ Минздрава России10.48612/agmu/2022.3.1.15.19kaspmed-4Research ArticleСтатьиСовременные серологические и иммунологические тесты для диагностики вирусных заболеванийModern serological and immunological tests for the diagnosis of viral diseaseАрнаудоваК. Ш.ArnaudovaK. Sh.

Кристина Шотаевна Арнаудова, кандидат медицинских наук, старший научный сотрудник, заместитель руко­водителя научно-исследовательского центра

Астрахань

 

Kristina Sh. Arnaudova, Candidate of Medical Sciences, Senior Researcher, Deputy Head of the Research Center

Astrakhan

 

arnaudova@mail.ruКопыловаМ. Р.KopylovaM. R.

Мария Романовна Копылова, научный сотрудник научно-исследовательского центра

Астрахань

Mariya R. Kopylova, Researcher, Research Center

Astrakhan

sydzymia1994@gmail.ruЖарковаЗ. В.ZharkovaZ. V.

Зинаида Владимировна Жаркова, научный сотрудник научно-исследовательского центра, ассистент кафедры ги­гиены медико-профилактического факультета с курсом последипломного образования

Астрахань

Zinaida V. Zharkova, Researcher of the Research Center, Assistant of the Department

Astrakhan

morikova21@mail.ruГенатуллинаГ. Н.GenatullinaG. N.

Гузель Наилевна Генатуллина, кандидат биологических наук, заместитель руководителя научно­-исследовательского центра, доцент кафедры фармакогнозии, фармацевтической технологии и био­технологии

Астрахань

Guzel' N. Genatullina, Cand. Sci (Biol.), Deputy Head of the Research Center, Associate Professor of the Department

Astrakhan

genatullina@mail.ruАстраханский государственный медицинский университетРоссияAstrakhan State Medical UniversityRussian Federation202211042025311519Copyright © Арнаудова К.Ш., Копылова М.Р., Жаркова З.В., Генатуллина Г.Н., 20252025Арнаудова К.Ш., Копылова М.Р., Жаркова З.В., Генатуллина Г.Н.Arnaudova K.S., Kopylova M.R., Zharkova Z.V., Genatullina G.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.kaspmed.ru/jour/article/view/4

Для скринингового исследования и прогнозирования иммунного ответа, а также для диагностики вирусных заболеваний разной чувствительности используются современные сероло­гические и иммунологические тесты. Приведенные методы играют важную роль в эпидемиологии и разработке вакцин, а также позволяют определять численность и разнообразие антител. Были выяв­лены наиболее популярные в медицинской практике методы иммуноферментного (ELISA), иммунохроматографического и иммунохемилюминесцентного анализов. Однако они используются в ограни­ченной степени для определения статуса инфекции (в сочетании с молекулярно-генетическими ана­лизами), серологической распространенности и статуса иммунной защиты медицинских работников.

Modern serological and immunological tests are used for screening studies and prediction of the immune response, as well as for the diagnosis of viral diseases of different sensitivity. These methods play an important role in epidemiology and vaccine development, and also allow determining the number and diversity of antibodies. The most popular methods of enzyme immunoassay (ELISA), immunochroma­tographic and immunochemiluminescent assays in medical practice were identified. However, they are used to a limited extent to determine the status of infection (in combination with molecular genetic analyses), se­rological prevalence and the status of immune protection of medical workers.

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The authors declare that there are no conflicts of interest present.