Longterm persistence of SARS-CoV-2 in a patient with infectious endocarditis and COVID-19: a clinical case
https://doi.org/10.17021/2712-8164-2024-3-28-33
Abstract
The literature contains isolated data on long-term persistence of the virus in the body in immunocompromised patients. The aim – to present a case of long-term persistence of SARS-CoV-2 in a patient with infective endocarditis. We retrospectively analysed the results of PCR assays for COVID-19 in a patient diagnosed with primary infective endocarditis and COVID-19. Despite the given therapy, the persistence of the virus in the patient amounted to 35 days. It was caused by infective endocarditis, a disease accompanied by changes in the organism's reactivity and immune response. COVID-19 affected the course of the postoperative period.
About the Authors
D. K. Tverdokhlebova
Federal Center of Cardiovascular Surgery
Россия
Россия
Diana K. Tverdokhlebova – Doctor of the Clinical Laboratory Diagnostics
Astrakhan
O. V. Petrova
Federal Center of Cardiovascular Surgery
Россия
Россия
Ol’ga V. Petrova – Dr. Sci. (Med.), Head of the Laboratory
Astrakhan
I. N. Litvinova
Federal Center of Cardiovascular Surgery
Россия
Россия
Irina N. Litvinova – Bacteriologist
Astrakhan
E. V. Smel’tsova
Federal Center of Cardiovascular Surgery
Россия
Россия
Ekaterina V. Smel’tsova – Medical Technologist
Astrakhan
O. O. Kurashenko
Federal Center of Cardiovascular Surgery
Россия
Россия
Ol’ga O. Kurashenko – Medical Technologist
Astrakhan
References
1. Li Y., Ji D., Cai W., Hu Y., Bai Y., Wu J., Xu J. Clinical characteristics, cause analysis and infectivity of COVID-19 nucleic acid repositive patients: A literature review. Journal of Medical Virology. 2021; 93 (3): 1288–1295. doi: 10.1002/jmv.26491.
2. Ao Z., Li Y., Wei J., Jiang J., Wang X., Zhang P., Liu Y., Yu H., Zhu L., Wang X., Hu Q., Duan J., Hu W., Zhang X., Wu G., Guo S. Clinical characteristics and potential factors for recurrence of positive SARS-CoV-2 RNA in convalescent patients: a retrospective cohort study. Clinical and Experimental Medicine. 2021; 21 (3): 361–367. doi: 10.1007/s10238-021-00687-y.
3. Wang Z., Feng Z., Tang S., Zeng J., Ning H., Huang C., Zhang L. Resurgence of Positive qRT-PCR Test Results in Patients Recovered from COVID-19: Case Reports. American Journal of The Medical Sciences. 2021; 361 (5): 650–654. doi: 10.1016/j.amjms.2021.01.019.
4. Huang K., Liu W., Zhou J., Wang Y., Zhang Y., Tang X., Liang J., Bi F.F. Repositive RT-PCR test in discharged COVID-19 patients during medical isolation observation. International Journal of Medical Sciences. 2021; 18 (12): 2545–2550. doi: 10.7150/ijms.58766.
5. Song K. H., Kim D. M., Lee H., Ham S. Y., Oh S. M., Jeong H., Jung J., Kang C. K., Park J. Y., Kang Y. M., Kim J. Y., Park J. S., Park K. U., Kim E. S., Kim H. B. Dynamics of viral load and anti-SARS-CoV-2 antibodies in patients with positive RT-PCR results after recovery from COVID-19. Korean Journal of Internal Medicine. 2021; 36 (1): 11–14. doi: 10.3904/kjim.2020.325.
6. Xia J., Zeng Y., Tan Z., Chen T., Hu W., Shuai S., Cao D., Zeng X. Differentials of SARS-CoV-2 Viral RNA Re-positivity in Discharged COVID-19 Patients. AIDS Reviews. 2021; 23 (3): 153–163. doi: 10.24875/AIDSRev.21000023.
7. Tang X., Musa S. S., Zhao S., He D. Reinfection or Reactivation of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review. Frontiers in Public Health. 2021; 9: 663045. doi: 10.3389/fpubh.2021.663045.
8. Kotova E. O., Pisaryuk A. S., Kobalava Zn. D., Timofeeva Yu. A., Chipigina N. S., Karaulova Yu. L., Ezhova L. G. Infective endocarditis and COVID-19 the impact of SARS-Co-V-2 infection on diagnostics, course, and prognosis. Russian Journal of Cardiology. 2023; 28 (1): 5229. doi: 10.15829/1560-4071-2023-5229. EDN FHVYGL.
9. Petrova O. V. Molekuljarnye prediktory oslozhnenij v rannem posleoperacionnom periode u kar-diohirurgicheskih bol'nyh = Molecular predictors of complications in the early postoperative period in cardiac surgery patients. Dissertation of Doctor of Medical Sciences. Astrakhan; 2022: 274 p. (In Russ).
10. Taghizadeh-Waghefi A., Petrov A., Wilbring M., Alexiou K., Kappert U., Matschke K., Tugtekin S.M. Cardiac surgery for treatment of COVID-19-associated infectious endocarditis. Texas Heart Institute Journal. 2023; 50 (2): e227884. doi: 10.14530/THIJ-22-7884.
11. Yang B., Cases J., Farhat L., Le T., Brown B., St Pierre E., Wu X., Kim K. V., Patei H. J., Deeb G. M. Root abscess in the setting of infections endocarditis: Short and long term outcome. Journal of Thoracic and Cardiovascular Surgery. 2021; 162 (4): 1049–1059. el. doi: 10.1016/j.tcvs. 2019.12.140.
12. Quintero-Martinez J. A., Hindy J. R., Mahmood M., Gerberi D. J., DeSimone D. C., Baddour L. M., A clinical profile of infective endocarditis in patients with recent COVID-19: A systematic review. American Journal of The Medical Sciences. 2022; 364 (1): 16–22. doi: 10.1016/j.amjms.2022.02.05.
Review
For citations:
Tverdokhlebova D.K., Petrova O.V., Litvinova I.N., Smel’tsova E.V., Kurashenko O.O. Longterm persistence of SARS-CoV-2 in a patient with infectious endocarditis and COVID-19: a clinical case. Title. 2024;5(3):28-33. (In Russ.) https://doi.org/10.17021/2712-8164-2024-3-28-33
Views:
148
JATS XML
Email this article 