Preview

Caspian Journal of Medicine and Pharmacy

Advanced search

Complex analysis of factors of compliance with bronchial asthma therapy in children and assessment of methodological approaches to improve its effectiveness

https://doi.org/10.17021/2712-8164-2026-2-25-30

Abstract

This study assessed treatment adherence in children with asthma, revealing that up to 90 % of patients exhibit low adherence associated with poor disease control. A single, individualized training session was shown to significantly reduce inhalation technique errors, especially when using metered-dose inhalers and nebulizers. The authors emphasize the need for comprehensive measures, including regular training and digital monitoring, to improve this situation. The aim of the study was to comprehensively assess treatment adherence in children with asthma, identify clinical, demographic, and organizational factors influencing it, and evaluate the effectiveness of educational interventions to correct inhalation technique errors. Materials and methods: A cross-sectional study included 30 children with bronchial asthma. Clinical and anamnestic data were collected, disease control was assessed using Asthma Control Test and the Morisky – Green adherence scale. Inhalation technique was analyzed using metered-dose inhalers, metered-dose powder inhalers, and nebulizers, followed by individual training and reassessment. Results: Most patients had low adherence (up to 90 % according to the Morisky – Green scale), and this indicator was practically independent of age and asthma severity, but was associated with an increased frequency of uncontrolled disease according to the results of asthma control tests, especially in moderate and severe asthma. Before training, the highest frequency of critical errors was observed with metered-dose powder inhalers and aerosol inhalers, whereas after a single individual training session, the proportion of patients without inhalation technique errors significantly increased, especially among users of metered-dose inhalers and nebulizers. Conclusion: Low adherence to asthma therapy in children is almost universal and requires comprehensive interventions, including regular inhalation skill assessment, individualized age-appropriate training, and the use of digital monitoring technologies.

About the Authors

D. F. Sergienko
Astrakhan State Medical University
Russian Federation

D. F. Sergienko, Dr. Sci. (Med.), Professor of the Department



M. V. Temereva
Astrakhan State Medical University
Russian Federation

M. V. Temereva, Resident of the Department



M. Z-A. Bersanova
Astrakhan State Medical University
Russian Federation

M. Z.-A. Bersanova, student



T. M. Kuznetsova
Regional Children's Clinical Hospital named after N. N. Silishcheva
Russian Federation

T. M. Kuznetsova, Pulmonologist



References

1. Clinical guidelines. Bronchial asthma in children. Russian Association of Allergologists and Clinical Immunologists, Russian Respiratory Society, Union of Pediatricians of Russia. Moscow; 2024. 146 p. (In Russ.).

2. Bronchial asthma. Clinical guidelines RF 2024. MedElement. URL: https://diseases.medelement.com/disease/бронхиальная-астма-дети (accessed: 17.02.2026) (In Russ.)

3. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. 2024. 234 p. URL: https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf (accessed: 17.02.2026).

4. Namazova-Baranova L. S., Geppe N. A., Malakhov A. B. Problems of therapy adherence in children with bronchial asthma. Pediatricheskaya farmakologiya = Pediatric pharmacology. 2020; 17 (3): 226–234 (In Russ.).

5. The role of adherence in achieving control of bronchial asthma in adolescents: possible strategies for solving the problem. Effektivnaya farmakoterapiya = Effective pharmacotherapy. 2024; (20): 18–24 (In Russ.).

6. Lukina Yu. V., Kutishenko N. P., Dmitrieva N. A., Martsevich S. Yu. Questionnaires and scales for assessing adherence to treatment: advantages and disadvantages of the diagnostic method in scientific research and real clinical practice. Kardiovaskulyarnaya terapiya i profilaktika = Cardiovascular therapy and prevention. 2020; 19 (4): 67–75 (In Russ.).

7. Liu A. H., Zeiger R., Sorkness C., Mahr T., Ostrom N., Burgess S., Rosenzweig J., Manjunath R. Development and cross-sectional validation of the Childhood Asthma Control Test. Journal of Allergy and Clinical Immunology. 2007; 119 (4): 817–825.

8. Nathan R., Sorkness C., Kosinski M., Schatz M., Li J. T., Marcus P. Development of the Asthma Control Test: a survey for assessing asthma control. Journal of Allergy and Clinical Immunology. 2004; 113 (1): 59–65.

9. Aysanov Z. R. Errors in the use of various types of inhalation devices in patients with broncho-obstructive diseases. Terapevticheskiy arkhiv = Therapeutic archive. 2023; 95 (1): 20–27 (In Russ.)

10. Propeller Health: a system for treating asthma and COPD. Evercare. 2019. URL: https://evercare.ru/sistema-dlya-lecheniya-astmy-i-khobl-ot-propeller (accessed: 17.02.2026) (In Russ.).


Review

For citations:


Sergienko D.F., Temereva M.V., Bersanova M.Z., Kuznetsova T.M. Complex analysis of factors of compliance with bronchial asthma therapy in children and assessment of methodological approaches to improve its effectiveness. Caspian Journal of Medicine and Pharmacy. 2026;7(2):25-30. (In Russ.) https://doi.org/10.17021/2712-8164-2026-2-25-30

Views: 145

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2712-8164 (Print)