The review describes the issues of the prevalence of cardiovascular diseases, their possible correction by synthetic and herbal drugs. Advantages of medicinal preparations based on vegetal raw materials over synthetic medicinal preparations are presented. The possibility of using a plant of the genus Astragalus to search for new phytopreparations as agents used in cardiac pathologies (arterial hypertension and chronic heart failure) is considered.
Modern serological and immunological tests are used for screening studies and prediction of the immune response, as well as for the diagnosis of viral diseases of different sensitivity. These methods play an important role in epidemiology and vaccine development, and also allow determining the number and diversity of antibodies. The most popular methods of enzyme immunoassay (ELISA), immunochromatographic and immunochemiluminescent assays in medical practice were identified. However, they are used to a limited extent to determine the status of infection (in combination with molecular genetic analyses), serological prevalence and the status of immune protection of medical workers.
The topic is due to the undoubted modernization of modern society, innovative improvement of processes in the healthcare system and medical science. The actualization is aimed at monitoring the demand for innovations, improving products, technologies, services, areas, related areas that ensure work taking into account the requirements of the volatility of the market situation.
Speaking about issues related to the formation of an innovative society, the need to generate and promote ideas university science is a resource area that multiplies the principles of intellectual and human capital, taking into account leading trends and the latest educational technologies. This analysis makes it possible to identify the principles of sustainable development by supporting units that perform the role of innovation management and technology transfer at all stages of the project life cycle, through continuous communication between science and practice, to increase the level of competitiveness and profitability of domestic developments, inventions and the development of an innovative healthcare system as a whole.
Progressive tracks, targets and strategic processes describe the opportunities to stimulate intellectual capital, apply key competencies and acquired skills, the potential for a performance-oriented implementation process, for continuous improvement in the areas of practical healthcare and population policy in accordance with the National Goals.
The study is devoted to the study of the immunotropic action of the combined extract from cumin sandy, small-flowered yarrow and licorice nude against the background of immunosuppression induced by the administration of hydrocortisone. The analysis of the obtained results showed that the introduction of the combined extract can weaken the suppressive effect of glucocorticosteroids on the parameters of peripheral blood, the macrophage link of immunity and immunocompetent organs, which makes it possible to recommend it for further study in order to create new plant immunomodulatory drugs.
The aim of the study: to establish the sanitary and parasitological condition of the water bodies of Astrakhan and the Astrakhan region.
Materials and methods. 2252 samples of water taken from various water sources in Astrakhan and rural areas of the Astrakhan region were studied. The number of samples that do not meet sanitary and hygienic standards was 2,3 %.
Research results. Water was taken from 2017 to 2021 both in urban and rural areas of the Astrakhan region from various water sources. Most of the studies were conducted in the city (72,6 %), 2,6 % of the samples did not meet the sanitary and parasitological standards. Eggs and larvae of helminths were found in these samples (larvae of strongylids 20 samples, eggs of toxocars 9 samples, ascarids and small tapeworms 1 sample each), as well as cysts of pathogenic intestinal protozoa (dysentery amoeba 7 samples and blastocysts 4 samples).
Conclusions. The sanitary and parasitological state of the water bodies of the Astrakhan region remains very tense, as evidenced by the above indicators. The parasitic contamination of water in the urban area is slightly higher than that in comparison with rural areas of the Astrakhan region. This indicates almost the same contamination of water bodies with the feces of invasive humans (eggs of ascaris, broad tapeworm, opisthorchis, cysts of dysentery amoeba, blastocysts) and animals (larvae of strongylids, eggs of toxocars), as well as possible flooding of water bodies due to accidents on the sewer network.
The article presents the results of the quantitative content of the sum of phenol carboxylic acids in the Salvia Stepposa Schost. feedstock. It was experimentally confirmed that the optimal extractant when extracting the sum of phenol carboxylic acids from the Salvia Stepposa Schost. feedstock. is 70 % ethyl alcohol. The maximum content of the sum of phenol carboxylic acids is noted in extracts obtained from samples of raw materials ground to particle size passing through a sieve with a diameter of holes of 2 mm. The content of the total phenol carboxylic acids is: in leaves 1,43 %, in flowers 1,22 % and in grass 1,74 %. The obtained experimental data can be used in the development of regulatory documentation for a new type of medicinal vegetal raw material “Sage of steppe grass”.
Over the past decade, the state budgetary healthcare institution “Aleksand-ro-Mariinsky Regional Clinical Hospital” (GBUZ JSC AMOKB) has conducted numerous telemedicine services. The main task of which was to consult a doctor online, which made it possible to identify the main positive aspects of the introduction of telemedicine in Astrakhan healthcare.
Remote monitoring of patients suffering from chronic pathologies, which is actively implemented by the State Medical Institution of JSC AMOKB, allows improving the overall quality of life of patients, reducing and rationally distributing the burden on medical staff. As part of telemedicine, patients receive in an accessible form the necessary information about their condition, the specifics of examination and treatment, and improved monitoring of compliance with doctor's prescriptions. Timely correction of prescribed treatment, increasing the effectiveness of drug therapy, increases the degree of awareness and medical literacy of patients, which reduces mortality among patients suffering from cardiovascular diseases and other common pathologies, reducing the number of hospitalizations, calls for emergency medical care.
The analysis of demographic processes is the necessary basis for the planning and implementation of State social programs, assessments of their effectiveness. The preservation and growth of the population is the most important state task, and the most important demographic indicators of its assessment, which are reflected in the National Projects. Changes in demographic indicators are inert, do not immediately respond to state measures and need to be monitored and evaluated. The most objective, isolated from external, including random factors, are the values of the indicators of the model demographic tables. The use of statistical methods to estimate the dynamics of calculated demographic values of demographictables allows us to assess demographic trends, plan and design development programs of the territory.
The article is devoted to a rare complication of cholelithiasis, namely, acute cholelithiasis obstruction. The paper describes in detail the treatment and diagnostic tactics of attachment. The clinical material of the practice is presented by cases of treatment of patient S., bom in 1946, hospitalized in the surgical department 2 weeks after the onset of the disease. When establishing the diagnosis, we were guided by the performance of laboratory and instrumental studies. Therapeutic tactics is based on surgical intervention with the elimination of intestinal obstruction at the first stage. Elimination of biliodigestive fistula was carried out in a planned manner. After the treatment, the patient's condition improved. Discharged in a satisfactory condition.
